Setup for taking a photo can be difficult and take alot of time. First you need to find a location. Do this before it gets dark. At least know the general location of where you want to take the photo, and check the bortle scale of the area. You will want to wait for astronimical twilight to start taking your photos. First you want to set up the tripod, make sure it is level on the ground. Then you can attatch the mount to the tripod and secure it. Then loosen the screws on the mounting base, remove it and attatch it to the ball head. Then reattatch the base to the mount, screwing the screws tight. Now mount the camera onto the ball mount. Next you can slot in the scope, and turn on the mount. Make sure the settings are on the correct hemisphere, and the tracking speed in 1x. You can now click the light button, and start looking for polaris through the scope. Line up the north star with the position it shows on the app using the knobs, so that you are now pointed directly at the north celestial pole. From here you just need to attach your shutter switch and set your settings. Play around with the following settings. Best of luck!
Here is iOptron's video on the Skytracker in case you get confused.